Vector Genetics Lab

Yoosook Lee
Yoosook Lee

Assistant Researcher
Department of Pathology, Microbiology and Immunology
School of Veterinary Medicine

University of California - Davis
One Shields Avenue
Davis, CA 95616
Phone: (530) 752-7333
Email: yoslee[at]

Research Interests
Research Experience
Honors and Awards


B.S in Life Science, Life Science Department, the Pohang University of Science and Technolgy (POSTECH), 2000

Ph.D. in Biology, Department of Ecology and Evolutionary Biology, University of California - Los Angeles, 2006

Posdoctoral Scholar, Department of Entomology, University of California - Davis, 2006-2007

Postdoctoral Scholar, UC Mosquito Research Program, Department of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California - Davis, 2007 - 2011

Research Interests

  • Population Genetics
  • Compuatational biology
  • Population Genomics Database

Research Experience

2006 -- 2011 Postdoctoral Researcher in Vector Genetics Lab at UC Davis
2001 -- 2006 Graduate Student Researcher in Adaptive Language Group at UCLA
1999 -- 2000 Research participant in Structural Biology Laboratory, POSTECH, Korea

Honors and Awards

Journal of Medical Entomology 2009 Editor's Choice Award for Lee et al. 2009. JME.
BioMed Central Open Data Award 2009 Winner at the 4th BioMed Central Annual Research Award, London, UK, Jun 10, 2010
Invited speaker for the Symposium, "Advances in Anopheles gambiae Population Genomics" at the 58th annual meeting of American Society of Tropical Medicine and Hygiene, Nov 18-22, 2009, Washington, DC, USA
Invited speaker for the Life Sciences Department Seminar Series, "Ecological and Genetic Relationship among members of Anopheles gambiae s.l.", POSTECH, Korea, Jun 16, 2009
The annual meeting of the Bioinformatics Resource Centers, NIAID, "Anopheles gambiae Population Genomics Database: Ground work for population genetic database", Deerfield Beach, Florida, Oct 28- 29, 2008
Speaker for UCLA Bioformatics IDP Research Conference, "Anopheles gambiae Population Genomics Database: Ground work for population genetic database", Skirball Cultural Center, Los Angeles, CA, USA, May 23, 2008
William C. Reeves New Investigator Award 3rd place winner, 2008 Mosquito and Vector Control Association of California Annual Conference.
Best Paper Award, 8th International conference on artificial life and robotics

Selected Publications

  1. Marsden CD, Lee Y, Kreppel K, Weakley A, Cornel A, Ferguson HM, Eskin E, Lanzaro GC. Diversity, differentiation and linkage disequilibrium: prospects for association mapping in the malaria vector, Anopheles arabiensis. G3. SUBMITTED.
  2. Lee Y, Marsden CD, Norris LC, Collier TC, Main Bradley, Fofana A, Cornel AJ, Lanzaro GC. Spatio-temporal dynamics of gene flow and hybrid fitness between the M and S forms of the malaria mosquito, Anopheles gambiae. PNAS. In Press.
  3. Lee Y, Marsden CD, Nieman C, Lanzaro GC. A new multiplex SNP genotyping assay for detecting hybridization and introgression between the M and S molecular forms of Anopheles gambiae. Mol Ecol Resourc. E-pub ahead of print.
  4. Sanford MR, Ramsay S, Cornel AJ, Marsden CD, Norris LC, Patchoke S, Fondjo E, Lanzaro GC, Lee Y. A preliminary investigation of the relationship between water quality and Anopheles gambiae larval habitats in western Cameroon. Malar J. 2013. 12:225. doi: 10.1186/1475-2875-12-225. PMCID: PMC3704728.
  5. Marsden CD, Cornel A, Lee Y, Sanford MR, Norris LC, Goodell PB, Nieman CC, Han S, Rodrigues A, Denis J, Ouledi A, Lanzaro GC. An analysis of two island groups as potential sites for trials of transgenic mosquitoes for malaria control. Evol Appl. 2013. DOI: 10.1111/eva.12056
  6. Lee Y, Collier TC, Sanford MR, Marsden CD, Fofana A, Cornel AJ, Lanzaro GC. Chromosome Inversions, Genomic Differentiation and Speciation in the African Malaria Mosquito Anopheles gambiae. PLoS One. 2013. 8(3): e57887. doi:10.1371/journal.pone.0057887
  7. Cornel AJ, Lee Y, Trout Fryxell RT, Seifert S, Nieman C, Lanzaro GC. Culex pipiens Sensu Lato in California: A Complex Within a Complex? J Am Mosq Control Assoc. 2012. 28 (4s):113-121.
  8. Fryxell RT, Seifert SN, Lee Y, Sacko A, Lanzaro G, Cornel A. The knockdown resistance mutation and knockdown time in Anopheles gambiae collected from Mali evaluated through a bottle bioassay and a novel insecticide-treated net bioassay. J Am Mosq Control Assoc. 2012. 28(2):119-22.
  9. Lee Y, Seifert SN, Nieman CS, McAbee RD, Goodell P, Fryxell RT, Lanzaro GC, Cornel AJ. High degree of single nucleotide polymorphisms in California Culex pipiens (Diptera:Culicidae) sensu lato. J Med Entomol. 2012. 49(2): 299-306.
  10. Lee Y, Seifert SN, Fornadel CM, Norris DE, Lanzaro GC. Single nucleotide polymorphisms for high-throughput genotyping of Anopheles arabiensis in East and Southern Africa. J Med Entomol. 2012. 49(2): 307-315.
  11. Trout Fryxell RT, Nieman CC, Fofana A, Lee Y, Traore SF, Cornel AJ, Luckhart S, Lanzaro GC Differential Plasmodium falciparum infection of Anopheles gambiae s.s. molecular and chromosomal forms in Mali Malaria J. 2012. 11:133.
  12. Demirci B, Lee Y, Lanzaro GC, B Alten. Identification and characterization of single nucleotide polymorphisms (SNPs) in Culex theileri Theobald (Diptera: Culicidae). J Med Entomol. 2012. 49(3): 581-588.

  13. Demirci B, Lee Y, Lanzaro GC, Alten B. Altitudinal genetic and morphometric variation among populations of Culex theileri Theobald (Diptera: Culicidae) from northeastern Turkey. J Vector Ecol. 2012 Jun;37(1):197-209. doi: 10.1111/j.1948-7134.2012.00217.x.
  14. Marsden CD, Lee Y, Neiman C, Sanford MR, Dinis J, Marins C, Rodrigues AR, Cornel AJ, Lanzaro GC. Asymmetric introgression between the M and S molecular forms of the malaria vector, Anopheles gambiae, maintains divergence despite extensive hybridisation. Mol Ecol. 2011. 20(23): 4983-4994.
  15. Ng'habi KR, Knos BGJ, Lee Y, Ferguson HM, Lanzaro GC. Population genetic structure of Anopheles arabiensis and Anopheles gambiae in a malaria endemic region of southern Tanzania. Malaria J. 2011. 10:289
  16. Sanford MR, Demirci B, Marsden CD, Lee Y, Cornel AJ, Lanzaro GC. Morphological Differentiation may Mediate Mate-Choice between Incipient Species of Anopheles gambiae s.s. PLoS One. 2011. 6(11): e27920.
  17. Horton A, Lee Y, Coulibaly C, Rashbrook VK, Cornel AJ, Lanzaro GC, Luckhart S. (2010) Identification of three single nucleotide polymorphism in Anopheles gambiae immune signaling genes that are associated with natural Plamodium falciparum infection. Malaria J. 2010 9:160.
  18. Lee Y, Cornel AJ, Meneses CR, Fofana A, Andrianarivo AG, McAbee RD, Fondjo E, Traoré SF, Lanzaro GC. Ecological and genetic relationships of the Forest-M form among chromosomal and molecular forms of the malaria vector Anopheles gambiae sensu stricto. Malaria J. 2009 8:75.
  19. Lee Y, Meneses CR, Fofana A, Lanzaro GC. Desiccation resistance among subpopulations of Anopheles gambiae s.s. from Selinkenyi, Mali. J Med Entomol. 2009 46(2):316-20.
  20. Lee Y, Collier TC, Taylor CE, Olfati-Saber R. Emergence of cohesion in the evolutionary dynamics of grammar networks. Evol Ecol Res. 2009. 11(5): 433-445.
  21. Jung KH, Lee J, Dardick C, Seo YS, Cao P, Canlas P, Phetsom J, Xu X, Ouyang S, An K, Cho YJ, Lee GC, Lee Y, An G, Ronald PC. (2008) Identification and functional analysis of light-responsive unique genes and gene family members in rice. PLoS Genet. 4(8):e1000164.
  22. Reimer L, Fondjo E, Patchoké S, Diallo B, Lee Y, Ng A, Ndjemai HM, Atangana J, Traore SF, Lanzaro G, Cornel AJ. Relationship between kdr mutation and resistance to pyrethroid and DDT insecticides in natural populations of Anopheles gambiae. J Med Entomol. 2008 45(2):260-6.
  23. Slotman MA, Tripet F, Cornel AJ, Meneses CR, Lee Y, Reimer LJ, Thiemann TC, Fondjo E, Fofana F, Traore SF, Lanzaro GC. Evidence for subdivision within the M molecular form of Anopheles gambiae. Mol Ecol. 2007 16(3):639-649
  24. Manoukis NC, Lee Y, Vallejo E, Taylor CE. Detecting recurrent extinction in a metapopulations of Anopheles gambiae: preliminary results using simulation. Proceedings of the 6th WSEAS International Conference on Algorithms, Scientific Computing, Modeling and Simulation. 2004
  25. Lee Y, Collier TC, Taylor CE, Stabler EP. Cohesion of languages in grammar networks. 2007. pp. 359-376 in Shamma, J., Cooperative Control of Distributed Multiagent Systems. Wiley-Interscience. Chichester, U.K.
  26. Lee Y, Collier TC, Kobele GM, Stabler EP, Taylor CE. Grammar Structure and the Dynamics of Language Evolution. 2005. pp 634-643 in Advances in Artificial Life. Proceedings of the VIIIth European Conference on Artificial Life. Canterbury, UK. September. Springer, Berlin
  27. Lee Y, Collier TC, Stabler EP, Taylor CE. The role of population structure in language evolution. 2004. in M. Sugisaka and H. Tanaka, eds., Proceedings of the Tenth International Symposium on Artificial Life and Robotics.
  28. Lee Y, Riggle J, Collier TC, Stabler EP, Taylor CE. Adaptive Communication among Collaborative Agents: Preliminary Results with Symbol Grounding. 2004. Artificial Life and Robotics, 8:127-132.
  29. Kobele GM, Riggle J, Collier TC, Taylor CE, Lee Y, Lin Y, Yao Y, Stabler EP. Grounding as Learning. 2003. Proceedings of the ESSLLI
  30. Stabler EP, Collier TC, Kobele GM, Taylor CE, Lee Y, Lin Y, Riggle J, Yao Y. The learning and emergence of mildly context sensitive languages. 2003. pp525-534 in W. Banzhaf, T. Christaller, P. Dittrich, J. T. Kim and J. Ziegler, eds. Advances in Artificial Life: 7th European Conference, ECAL 2003. Springer, Berlin.


The Effect of Structure in Population and Grammar Space on Language Divergence. Yoosook Lee, Ph.D. Department of Ecology and Evolutionary Biology, UCLA