UC Davis School of Veterinary Medicine

School of Veterinary Medicine


   
Portrait Leslie A. Lyons

Professor of Genetics
School of Veterinary Medicine
Population Health and Reproduction
4206 Vet Med 3A (mailing address)
260 Center for Companion Animal Health (CCAH) (Office)
Office 530-754-5546 Lab 530-754-2287 (75 4-CATS)
Email: lalyons@ucdavis.edu
   
Research
The research laboratory of Professor Leslie Lyons at UC Davis is located in the Center for Companion Animal Health (CCAH). Research focuses on the genetics of the domestic cat and the development of genetic tools and resources that assist gene mapping in the cat and other companion animals. Feline research is focused on the discovery of mutations that cause inherited diseases and phenotypic traits and in the population dynamics of breed development and domestic cat evolution.
   
Teaching
Genetics: animal, veterinary, molecular, VMD 425 Veterinary Genetics
   
Service
Graduate Groups in Genetics, Animal Biology, Forensics
   
Personal Interests
Any Pittsburgh sports team, car racing, SCUBA diving, skiing, basketball, softball, classic movies, James Bond
   
Links

The Lyons' Den
The research laboratory of Professor Leslie Lyons at UC Davis is located in the Center for Companion Animal Health (CCAH). Research focuses on the genetics of the domestic cat and the development of genetic tools and resources that assist gene mapping in the cat and other companion animals. Feline research is focused on the discovery of mutations that cause inherited diseases and phenotypic traits and in the population dynamics of breed development and domestic cat evolution.

Laboratory Personnel:
Robert Grahn, Jennifer Grahn, Genesio Karere, Leslie Bach, Jennifer Kurishma, Tina Huang, Barbara Gandolfi, Kari Lee, Mike Hamilton

Lyons' Lab

   
Recent Publications

National Geographic – Explorer “The Science of Cats”  http://channel.nationalgeographic.com/series/explorer/3103/Photos#tab-Overview


Shin T, Kraemer D, Pryor J, Liu L, Rugila J, Howe L, Buck S, Murphy K, Lyons LA and M Westhusin. 2002. Cell biology: A cat cloned by nuclear transplantation. Nature. 415 (6874):859

Lyons LA, Biller DS, Erdman CA, Lipinski MJ, Young AE, Roe BA, Qin B, Grahn RA. Feline polycystic kidney disease mutation identified in PKD1.  J Am Soc Nephrol 15:2548-2555, 2004. PMID: 15466259.

Gómez MC, Pope EC, Giraldo A, Lyons LA, Harris RF, King AL, Cole A, Godke RA, Dresser BA. Birth and characteristics of African wildcat cloned kittens born from domestic cats.  Cloning Stem Cells 6:247-258, 2004. PMID: 15671671.

Lyons LA, Imes DL, Rah HC, Grahn RA. Tyrosinase mutations associated with Siamese and Burmese patterns in the domestic cat (Felis catus).  Anim Genet 36:119-26, 2005. PMID: 15771720.

Rah H, Maggs DJ, Blankenship TN, Narfstrom K, Lyons LA. Early-onset autosomal recessive progressive retinal atropy in Persian cats.  Invest Ophthalmol Visual Sci 46:1742-7, 2005. PMID: 15851577.

Lyons LA, Foe IT, and Grahn RA.  Chocolate coated cats: TYRP1 mutations for brown color in domestic cats.  Mammalian Genome 16:356-66, 2005. PMID: 16104383.

Lipinski MJ, et al. An international parentage and identification panel for the domestic cat (Felis catus). Anim Genet, 38(4): 371-377, 2007. PMC1974777.

Bighignoli B, Niini T, Grahn RA, Pedersen NC, Millon LV, Polli M, Longeri M, Lyons LA. Cytidine monophospho-N-acetylneuraminic acid hydrosylase (CMAH) mutations associated with the domestic cat AB blood group. BioMed Central, 8(27): 1471-2156, 2007. PMC1913925.

Karere GM, Froenicke L, Millon LV, Womack JE, Lyons LA.  A high-resolution radiation hybrid map of rhesus macaque chromosome 5 identifies rearrangements in the genome assembly. Genomics. (in press).

Lipinski MJ, Froenicke L, Baysac KC, Billings NC, Leutenegger CM, Levy AM, Longeri M, Niini T, Ozpinar H, Slater MR, Pedersen NC, Lyons LA. The ascent of cat breeds: Genetic evaluations of breeds and worldwide random-bred populations. Genomics, 91(1): 12-21, 2008. Epub 2007 Dec. PMC2267438.